General Fusion Inc.
Vancouver
General Fusion Inc. is a Vancouver-based company that has spent more than two decades chasing practical fusion. On June 9, 2026, it was ranked number one on TIME's list of the World's Top GreenTech Companies of 2026. The company is advancing toward becoming the first publicly traded pure-play fusion company through a proposed business combination with Spring Valley Acquisition Corp. III. It is pursuing a Magnetized Target Fusion (MTF) approach and has been operating its Lawson Machine 26 (LM26) demonstration machine since early 2025.
Xcimer Energy
Xcimer Energy is a fusion startup that has developed the Phoenix laser system, which it claims is the world's largest privately owned laser. The company's approach to fusion power is modeled after the National Ignition Facility, aiming to use more powerful, less complex lasers to create a profitable fusion power solution. Xcimer plans to complete a prototype in 2028 and build its first commercial scale power plant in the mid-2030s.
GRAIL, Inc.
GT Biopharma
Holmusk
Holmusk is a healthcare data science company powering NeuroBlu, a longitudinal neurology and behavioral health real-world data platform serving life sciences, biopharma, and biotech organizations. NeuroBlu provides de-identified patient data across mental health, neurology, and neurodegenerative conditions, enabling cohort discovery, outcomes measurement, and evidence-generation workflows for life sciences customers.
E
Eascra Biotech
Eascra Biotech is advancing the next generation of targeted cancer treatments through the development of Janus base nanomaterials (JBNs). They are advancing two commercial cancer therapies: a JBN‑based chemotherapy and a JBN‑based immunotherapy designed to precisely target solid tumors.